MELBOURNE (TIP): In a breakthrough, researchers have developed a revolutionary new way to manufacture natural chemicals and used it to assemble a scarce anti-inflammatory drug with potential to treat cancer and malaria. The advance could lead to new and cheaper ways to produce rare drugs in large quantities. “We took small molecules and clipped them together like Lego,” said lead researcher professor Michael Sherburn, from the Australian National University (ANU).
“The building blocks are carefully designed in such a way that the first reaction generates a product perfectly primed for the second. It’s quite magical. This means you can efficiently build large and complex molecules,” said Sherburn. Medicines of this type have traditionally been made in a cumbersome way. Chemists take a related molecule and renovate it. This is a lengthy process, with unwanted structural features being ripped out and replaced. “This leads to a lot of waste,” Sherburn said. The group trialled their innovative new method by making pseudopterosin, a powerful antiinflammatory and analgesic drug, which is currently only available in tiny quantities extracted from fan coral found in the Bahamas.
The work began as blue-sky research, with the researchers trying to work out a way to make supposedly impossible molecules of crossconjugated hydrocarbons. Before trying the experiments the team ran simulations on the Raijin supercomputer, which indicated that their method had potential. “Ours is an empowering and enabling technique, allowing a smarter and faster way to make important substances,” said Dr Chris Newton, who did the research in the laboratory as a PhD student. “The pseudopterosin synthesis is the tip of the iceberg. We are well on the way to efficient syntheses of other important drugs. “There is a potential for industrial-scale manufacture, too, which will take the pressure off species which are being harvested for drugs,” Newton said.
Its fantastic as your other blog posts : D, thanks for putting up.
I genuinely value your piece of work, Great post.
Valuable info. Fortunate me I found your web site accidentally, and I am shocked why this accident did not happened earlier! I bookmarked it.
Hello, i think that i saw you visited my website so i came to “return the favor”.I am trying to find things to improve my site!I suppose its ok to use a few of your ideas!!
Great wordpress blog here.. It’s hard to find quality writing like yours these days. I really appreciate people like you! take care
of course like your web-site but you have to check the spelling on several of your posts. Many of them are rife with spelling issues and I in finding it very troublesome to tell the reality on the other hand I¦ll surely come back again.
Attractive element of content. I simply stumbled upon your web site and in accession capital to claim that I get actually enjoyed account your blog posts. Any way I will be subscribing to your feeds and even I fulfillment you access consistently fast.
Have you ever thought about writing an e-book or guest authoring on other websites? I have a blog centered on the same information you discuss and would really like to have you share some stories/information. I know my readers would value your work. If you are even remotely interested, feel free to shoot me an email.
Absolutely pent subject material, thanks for information. “Life is God’s novel. Let him write it.” by Isaac Bashevis Singer.
Write more, thats all I have to say. Literally, it seems as though you relied on the video to make your point. You clearly know what youre talking about, why waste your intelligence on just posting videos to your blog when you could be giving us something informative to read?
I reckon something genuinely special in this web site.
I’m not sure why but this website is loading very slow for me. Is anyone else having this issue or is it a issue on my end? I’ll check back later and see if the problem still exists.
magnificent issues altogether, you simply gained a emblem new reader. What might you recommend in regards to your post that you made a few days in the past? Any positive?
An interesting dialogue is value comment. I feel that it’s best to write more on this topic, it won’t be a taboo subject but generally persons are not sufficient to talk on such topics. To the next. Cheers
Fantastic website you have here but I was curious if you knew of any forums that cover the same topics talked about in this article? I’d really love to be a part of online community where I can get feedback from other knowledgeable individuals that share the same interest. If you have any recommendations, please let me know. Thanks!
Very interesting subject, thanks for posting.
Great website. A lot of useful information here. I¦m sending it to several pals ans additionally sharing in delicious. And naturally, thank you for your effort!
I have been surfing online greater than 3 hours lately, but I by no means found any attention-grabbing article like yours. It is pretty price enough for me. In my opinion, if all site owners and bloggers made excellent content as you did, the net will probably be a lot more useful than ever before.
As soon as I found this web site I went on reddit to share some of the love with them.
This web site is really a walk-through for all of the info you wanted about this and didn’t know who to ask. Glimpse here, and you’ll definitely discover it.
I truly appreciate this post. I¦ve been looking all over for this! Thank goodness I found it on Bing. You’ve made my day! Thanks again
After I initially commented I clicked the -Notify me when new comments are added- checkbox and now every time a remark is added I get four emails with the identical comment. Is there any manner you can take away me from that service? Thanks!
I’m curious to find out what blog system you have been working with? I’m having some minor security problems with my latest site and I’d like to find something more safeguarded. Do you have any recommendations?
I am always looking online for ideas that can aid me. Thx!
Wonderful goods from you, man. I have understand your stuff previous to and you’re just extremely wonderful. I actually like what you’ve acquired here, certainly like what you are stating and the way in which you say it. You make it enjoyable and you still take care of to keep it sensible. I cant wait to read far more from you. This is actually a wonderful site.
Thank you for your whole hard work on this web site. My aunt loves doing research and it’s really easy to understand why. We all hear all concerning the compelling medium you make important information via the web site and therefore cause participation from other people about this subject while my girl is without question discovering a whole lot. Enjoy the rest of the new year. You’re conducting a useful job.
you are really a good webmaster. The site loading speed is amazing. It seems that you’re doing any unique trick. Also, The contents are masterwork. you have done a fantastic job on this topic!