Humans spend nearly a third of our lives asleep, yet sleep is anything but wasted time. Far from being passive downtime, it is an active and essential process that helps restore the body and protect the brain. When sleep is disrupted, the brain feels the consequences – sometimes in subtle ways that accumulate over years.
In a new study, researchers examined sleep behaviour and detailed brain MRI scan data in more than 27,000 UK adults between the ages of 40 and 70. They found that people with poor sleep had brains that appeared significantly older than expected based on their actual age. While people grow chronologically older at the same pace, some people’s biological clocks can tick faster or slower than others. New advances in brain imaging and artificial intelligence allow researchers to estimate a person’s brain age based on patterns in brain MRI scans, such as loss of brain tissue, thinning of the cortex and damage to blood vessels.
In the study, brain age was estimated using over 1,000 different imaging markers from MRI scans. The experts first trained a machine learning model on the scans of the healthiest participants – people with no major diseases, whose brains should closely match their chronological age. Once the model “learned” what normal ageing looks like, they applied it to the full study population. Having a brain age higher than your actual age can be a signal of departure from healthy ageing. Previous research has linked an older-appearing brain to faster cognitive decline, greater dementia risk and even higher risk of early death. Sleep is complex, and no single measure can tell the whole story of a person’s sleep health. The study, therefore, focused on five aspects of sleep self-reported by the study participants: their chronotype (“morning” or “evening” person), how many hours they typically sleep (seven to eight hours is considered optimal), whether they experience insomnia, whether they snore and whether they feel excessively sleepy during the day.
Be the first to comment