A virus that cause respiratory illnesses and stomach upsets in children could help in the fight against primary liver cancer, according to a study. Reovirus stimulates the body’s own immune system to kill off the cancerous cells and is also able to kill off the hepatitis C virus – a common cause of primary liver cancer – at the same time, the researchers at the University of Leeds discovered.
These early stage findings are important because primary liver cancer is the third highest cause of cancer deaths worldwide and, if surgery is not an option, the prognosis is poor. Study co-leader Dr Stephen Griffin, Associate Professor of Viral Oncology at the University of Leeds, said: “Ultimately we hope that by simultaneously treating the tumor, and the hepatitis virus that is driving the growth of the tumor, we may provide a more effective therapy and improve the outcomes for patients.
“Current treatments for liver cancer that can’t be removed by surgery are mainly palliative with chemotherapy only tending to prolong life, rather than cure and it can have significant side effects.” The University of Leeds team found that Reovirus was successful in treating both liver cancer cells grown in the laboratory and those taken directly from patients undergoing surgery.
When introduced into the body, Reovirus stimulates an immune system factor known as interferon, which in turn causes the activation of a specific white blood cell called a Natural Killer cell. These Natural Killer cells then kill both the tumor, and cells infected with the hepatitis C virus.
Stimulating the immune system to kill cancer cells is known as immunotherapy. It differs from chemotherapy, in which the actual drugs kill the cancer cells. The researchers are now hoping to start the first in-human clinical trials. Study co-leader Professor Alan Melcher, now Professor of Translational Immunotherapy at the Institute of Cancer Research, London, said: “Our study establishes a completely new type of viral immunotherapy for the most common primary liver cancer type, hepatocellular carcinoma, which has a very poor prognosis in its advanced form.
Attractive section of content. I just stumbled upon your site and in accession capital to assert that I get actually enjoyed account your blog posts. Anyway I will be subscribing to your feeds and even I achievement you access consistently quickly.
naturally like your web site but you have to check the spelling on quite a few of your posts. Many of them are rife with spelling problems and I to find it very bothersome to inform the reality on the other hand I will surely come again again.
Hi, just required you to know I he added your site to my Google bookmarks due to your layout. But seriously, I believe your internet site has 1 in the freshest theme I??ve came across. It extremely helps make reading your blog significantly easier.
I’m often to running a blog and i actually appreciate your content. The article has really peaks my interest. I am going to bookmark your site and keep checking for new information.
Very interesting subject, appreciate it for posting.
This is a topic close to my heart cheers, where are your contact details though?
Great post. I was checking constantly this weblog and I’m inspired! Very useful information particularly the ultimate section :) I take care of such information much. I was looking for this particular information for a long time. Thank you and good luck.
Hello. remarkable job. I did not expect this. This is a excellent story. Thanks!
Hi there would you mind letting me know which web host you’re using? I’ve loaded your blog in 3 completely different browsers and I must say this blog loads a lot quicker then most. Can you suggest a good hosting provider at a honest price? Kudos, I appreciate it!
Absolutely indited subject material, Really enjoyed looking at.
As a Newbie, I am constantly searching online for articles that can benefit me. Thank you
Thanks a bunch for sharing this with all of us you really know what you’re talking about! Bookmarked. Please also visit my site =). We could have a link exchange arrangement between us!
Hello, Neat post. There is an issue with your web site in web explorer, might test this?K IE nonetheless is the marketplace chief and a good element of folks will miss your excellent writing due to this problem.
Wow! This can be one particular of the most useful blogs We have ever arrive across on this subject. Basically Excellent. I am also a specialist in this topic so I can understand your effort.
I love your blog.. very nice colors & theme. Did you create this website yourself? Plz reply back as I’m looking to create my own blog and would like to know wheere u got this from. thanks
This internet site is my inhalation, really fantastic design and style and perfect subject matter.
Great post. I am facing a couple of these problems.
Well I sincerely liked studying it. This information offered by you is very effective for accurate planning.
I loved as much as you will receive carried out right here. The sketch is tasteful, your authored material stylish. nonetheless, you command get bought an shakiness over that you wish be delivering the following. unwell unquestionably come more formerly again as exactly the same nearly a lot often inside case you shield this increase.
Thankyou for this post, I am a big big fan of this internet site would like to keep updated.
Great line up. We will be linking to this great article on our site. Keep up the good writing.
My programmer is trying to persuade me to move to .net from PHP. I have always disliked the idea because of the costs. But he’s tryiong none the less. I’ve been using WordPress on numerous websites for about a year and am nervous about switching to another platform. I have heard excellent things about blogengine.net. Is there a way I can import all my wordpress posts into it? Any kind of help would be really appreciated!
Hello my friend! I wish to say that this post is awesome, nice written and include approximately all important infos. I’d like to see more posts like this .
Thank you for another fantastic article. Where else could anybody get that kind of info in such an ideal way of writing? I’ve a presentation next week, and I’m on the look for such info.
hey there and thanks on your info – I’ve definitely picked up anything new from right here. I did alternatively experience several technical points using this website, since I skilled to reload the web site lots of occasions prior to I could get it to load properly. I have been wondering in case your hosting is OK? Not that I’m complaining, but slow loading circumstances instances will sometimes impact your placement in google and could harm your high-quality rating if ads and ***********|advertising|advertising|advertising and *********** with Adwords. Well I’m adding this RSS to my e-mail and can glance out for much more of your respective fascinating content. Make sure you replace this again soon..
I was examining some of your blog posts on this internet site and I believe this web site is rattling informative ! Keep on posting.
I reckon something truly special in this website.
With everything which appears to be building within this particular subject material, all your viewpoints are relatively refreshing. On the other hand, I appologize, because I can not give credence to your whole suggestion, all be it exhilarating none the less. It would seem to everybody that your remarks are generally not completely justified and in actuality you are yourself not really completely certain of the argument. In any event I did take pleasure in reading through it.
Excellent site. Lots of useful info here. I am sending it to a few pals ans additionally sharing in delicious. And obviously, thank you in your effort!
You actually make it appear so easy along with your presentation however I find this matter to be actually one thing that I feel I would never understand. It sort of feels too complicated and very broad for me. I’m looking ahead on your subsequent post, I will try to get the dangle of it!
Perfect work you have done, this site is really cool with excellent info .
Howdy very nice blog!! Man .. Beautiful .. Amazing .. I’ll bookmark your web site and take the feeds also…I’m glad to find numerous useful info here within the submit, we need develop extra strategies in this regard, thanks for sharing. . . . . .